1EYE
1.7 ANGSTROM RESOLUTION CRYSTAL STRUCTURE OF 6-HYDROXYMETHYL-7,8-DIHYDROPTEROATE SYNTHASE (DHPS) FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH 6-HYDROXYMETHYLPTERIN MONOPHOSPHATE
Summary for 1EYE
| Entry DOI | 10.2210/pdb1eye/pdb |
| Related | 1ad1 1ad4 1aj0 1aj2 1ajz |
| Descriptor | DIHYDROPTEROATE SYNTHASE I, MAGNESIUM ION, PTERIN-6-YL-METHYL-MONOPHOSPHATE, ... (4 entities in total) |
| Functional Keywords | alpha-beta barrel, transferase |
| Biological source | Mycobacterium tuberculosis H37Rv |
| Total number of polymer chains | 1 |
| Total formula weight | 29170.36 |
| Authors | Baca, A.M.,Sirawaraporn, R.,Turley, S.,Sirawaraporn, W.,Hol, W.G.J. (deposition date: 2000-05-05, release date: 2000-10-11, Last modification date: 2024-03-13) |
| Primary citation | Baca, A.M.,Sirawaraporn, R.,Turley, S.,Sirawaraporn, W.,Hol, W.G. Crystal structure of Mycobacterium tuberculosis 7,8-dihydropteroate synthase in complex with pterin monophosphate: new insight into the enzymatic mechanism and sulfa-drug action. J.Mol.Biol., 302:1193-1212, 2000 Cited by PubMed: 11007651DOI: 10.1006/jmbi.2000.4094 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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