1EXX
ENANTIOMER DISCRIMINATION ILLUSTRATED BY CRYSTAL STRUCTURES OF THE HUMAN RETINOIC ACID RECEPTOR HRARGAMMA LIGAND BINDING DOMAIN: THE COMPLEX WITH THE INACTIVE S-ENANTIOMER BMS270395.
Summary for 1EXX
Entry DOI | 10.2210/pdb1exx/pdb |
Related | 1EXA 2LBD 3LBD 4LBD |
Descriptor | RETINOIC ACID RECEPTOR GAMMA-2, 3-FLUORO-4-[2-HYDROXY-2-(5,5,8,8-TETRAMETHYL-5,6,7,8,-TETRAHYDRO-NAPHTALEN-2-YL)-ACETYLAMINO]-BENZOIC ACID, DODECYL-ALPHA-D-MALTOSIDE, ... (4 entities in total) |
Functional Keywords | enantiomer discrimination, retinoid ligand complexes, antiparallel alpha-helical sandwich fold, structural proteomics in europe, spine, structural genomics, gene regulation |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 28800.57 |
Authors | Klaholz, B.P.,Mitschler, A.,Belema, M.,Zusi, C.,Moras, D.,Structural Proteomics in Europe (SPINE) (deposition date: 2000-05-05, release date: 2000-06-09, Last modification date: 2024-02-07) |
Primary citation | Klaholz, B.P.,Mitschler, A.,Belema, M.,Zusi, C.,Moras, D. Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma. Proc.Natl.Acad.Sci.USA, 97:6322-6327, 2000 Cited by PubMed: 10841540DOI: 10.1073/pnas.97.12.6322 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.67 Å) |
Structure validation
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