1EXA

ENANTIOMER DISCRIMINATION ILLUSTRATED BY CRYSTAL STRUCTURES OF THE HUMAN RETINOIC ACID RECEPTOR HRARGAMMA LIGAND BINDING DOMAIN: THE COMPLEX WITH THE ACTIVE R-ENANTIOMER BMS270394.

Summary for 1EXA

Entry DOI	10.2210/pdb1exa/pdb
Related	1EXX 2LBD 3LBD 4LBD
Descriptor	RETINOIC ACID RECEPTOR GAMMA-2, R-3-FLUORO-4-[2-HYDROXY-2-(5,5,8,8-TETRAMETHYL-5,6,7,8,-TETRAHYDRO-NAPHTALEN-2-YL)-ACETYLAMINO]-BENZOIC ACID, DODECYL-ALPHA-D-MALTOSIDE, ... (4 entities in total)
Functional Keywords	enantiomer discrimination, retinoid ligand complexes, antiparallel alpha-helical sandwich fold, structural proteomics in europe, spine, structural genomics, gene regulation
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	28800.57
Authors	Klaholz, B.P.,Mitschler, A.,Belema, M.,Zusi, C.,Moras, D.,Structural Proteomics in Europe (SPINE) (deposition date: 2000-05-02, release date: 2000-06-09, Last modification date: 2023-08-09)
Primary citation	Klaholz, B.P.,Mitschler, A.,Belema, M.,Zusi, C.,Moras, D. Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma. Proc.Natl.Acad.Sci.USA, 97:6322-6327, 2000 Cited by PubMed: 10841540 DOI: 10.1073/pnas.97.12.6322 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.59 Å)

Structure validation