1EXA

ENANTIOMER DISCRIMINATION ILLUSTRATED BY CRYSTAL STRUCTURES OF THE HUMAN RETINOIC ACID RECEPTOR HRARGAMMA LIGAND BINDING DOMAIN: THE COMPLEX WITH THE ACTIVE R-ENANTIOMER BMS270394.

1EXA の概要

• エントリーDOI: 10.2210/pdb1exa/pdb
• 関連するPDBエントリー: 1EXX 2LBD 3LBD 4LBD
• 分子名称: RETINOIC ACID RECEPTOR GAMMA-2, R-3-FLUORO-4-[2-HYDROXY-2-(5,5,8,8-TETRAMETHYL-5,6,7,8,-TETRAHYDRO-NAPHTALEN-2-YL)-ACETYLAMINO]-BENZOIC ACID, DODECYL-ALPHA-D-MALTOSIDE, ... (4 entities in total)
• 機能のキーワード: enantiomer discrimination, retinoid ligand complexes, antiparallel alpha-helical sandwich fold, structural proteomics in europe, spine, structural genomics, gene regulation
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28800.57

構造登録者

Klaholz, B.P.,Mitschler, A.,Belema, M.,Zusi, C.,Moras, D.,Structural Proteomics in Europe (SPINE) (登録日: 2000-05-02, 公開日: 2000-06-09, 最終更新日: 2023-08-09)

• 主引用文献: Klaholz, B.P.,Mitschler, A.,Belema, M.,Zusi, C.,Moras, D.; Enantiomer discrimination illustrated by high-resolution crystal structures of the human nuclear receptor hRARgamma.; Proc.Natl.Acad.Sci.USA, 97:6322-6327, 2000; PubMed: 10841540; DOI: 10.1073/pnas.97.12.6322

実験手法

X-RAY DIFFRACTION (1.59 Å)