1EV8
CRYSTAL STRUCTURE ANALYSIS OF CYS167 MUTANT OF ESCHERICHIA COLI
Summary for 1EV8
| Entry DOI | 10.2210/pdb1ev8/pdb |
| Related | 1EV5 1EVF 1EVG |
| Descriptor | THYMIDYLATE SYNTHASE (2 entities in total) |
| Functional Keywords | cys167 e. coli thymidylate synthase, transferase |
| Biological source | Escherichia coli |
| Cellular location | Cytoplasm : P0A884 |
| Total number of polymer chains | 1 |
| Total formula weight | 30880.20 |
| Authors | Phan, J.,Mahdavian, E.,Nivens, M.C.,Minor, W.,Berger, S.,Spencer, H.T.,Dunlap, R.B.,Lebioda, L. (deposition date: 2000-04-19, release date: 2000-05-03, Last modification date: 2022-04-13) |
| Primary citation | Phan, J.,Mahdavian, E.,Nivens, M.C.,Minor, W.,Berger, S.,Spencer, H.T.,Dunlap, R.B.,Lebioda, L. Catalytic cysteine of thymidylate synthase is activated upon substrate binding. Biochemistry, 39:6969-6978, 2000 Cited by PubMed: 10841779DOI: 10.1021/bi000367g PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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