1ELE
STRUCTURAL ANALYSIS OF THE ACTIVE SITE OF PORCINE PANCREATIC ELASTASE BASED ON THE X-RAY CRYSTAL STRUCTURES OF COMPLEXES WITH TRIFLUOROACETYL-DIPEPTIDE-ANILIDE INHIBITORS
Summary for 1ELE
Entry DOI | 10.2210/pdb1ele/pdb |
Related | 1ELD |
Related PRD ID | PRD_000360 |
Descriptor | ELASTASE, N-(trifluoroacetyl)-L-valyl-N-[4-(trifluoromethyl)phenyl]-L-alaninamide, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, serine proteinase, hydrolase/hydrolase inhibitor |
Biological source | Sus scrofa (pig) |
Cellular location | Secreted: P00772 |
Total number of polymer chains | 1 |
Total formula weight | 26491.51 |
Authors | Mattos, C.,Petsko, G.A.,Ringe, D. (deposition date: 1994-10-24, release date: 1995-02-14, Last modification date: 2024-06-05) |
Primary citation | Mattos, C.,Giammona, D.A.,Petsko, G.A.,Ringe, D. Structural analysis of the active site of porcine pancreatic elastase based on the X-ray crystal structures of complexes with trifluoroacetyl-dipeptide-anilide inhibitors. Biochemistry, 34:3193-3203, 1995 Cited by PubMed: 7880814DOI: 10.1021/bi00010a008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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