1EFN

HIV-1 NEF PROTEIN IN COMPLEX WITH R96I MUTANT FYN SH3 DOMAIN

1EFN の概要

• エントリーDOI: 10.2210/pdb1efn/pdb
• 分子名称: FYN TYROSINE KINASE, HIV-1 NEF PROTEIN, TRIMETHYL LEAD ION, ... (4 entities in total)
• 機能のキーワード: complex (sh3 domain-viral enhancer), proto-oncogene, transferase, tyrosine-protein kinase, phosphorylation, aids, myristylation, gtp-binding, atp-binding, sh3 domain, sh2 domain, ppii helix, pxxp motif, complex (sh3 domain-viral enhancer) complex, complex (sh3 domain/viral enhancer)
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane: P06241; Host cell membrane; Lipid-anchor; Cytoplasmic side (By similarity): P03406
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 49427.04

構造登録者

Lee, C.-H.,Kuriyan, J. (登録日: 1996-06-29, 公開日: 1997-01-11, 最終更新日: 2024-02-07)

• 主引用文献: Lee, C.H.,Saksela, K.,Mirza, U.A.,Chait, B.T.,Kuriyan, J.; Crystal structure of the conserved core of HIV-1 Nef complexed with a Src family SH3 domain.; Cell(Cambridge,Mass.), 85:931-942, 1996; PubMed: 8681387; DOI: 10.1016/S0092-8674(00)81276-3

実験手法

X-RAY DIFFRACTION (2.5 Å)