1EEL
STRUCTURE OF A COMPLEX BETWEEN THE DNA SEQUENCE DCGCGAATTCGCG AND BIS[PIPERIDINO-ETHYL]-FURAMIDINE
Summary for 1EEL
Entry DOI | 10.2210/pdb1eel/pdb |
Descriptor | 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', 2,5-BIS-[4-[CYCLOPENTA-1,3-DIEN-5-YLAMINO-1-AMINOMETHYL]-PHEN-1-YL]FURAN (3 entities in total) |
Functional Keywords | minor groove binding ligand, b-dna, bulky side-chains, dna |
Total number of polymer chains | 2 |
Total formula weight | 7763.33 |
Authors | Neidle, S.,Simpson, I.J. (deposition date: 2000-02-01, release date: 2000-02-09, Last modification date: 2024-04-03) |
Primary citation | Mazur, S.,Tanious, F.A.,Ding, D.,Kumar, A.,Boykin, D.W.,Simpson, I.J.,Neidle, S.,Wilson, W.D. A thermodynamic and structural analysis of DNA minor-groove complex formation. J.Mol.Biol., 300:321-337, 2000 Cited by PubMed: 10873468DOI: 10.1006/jmbi.2000.3869 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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