1EED

X-ray crystallographic analysis of inhibition of endothiapepsin by cyclohexyl renin inhibitors

1EED の概要

• エントリーDOI: 10.2210/pdb1eed/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000265
• 分子名称: ENDOTHIAPEPSIN, (2S)-2-[[(3S,4S)-5-cyclohexyl-4-[[(4S,5S)-5-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxidanyl-6-phenyl-hexanoyl]amino]-3-oxidanyl-pentanoyl]amino]-4-methyl-pentanoic acid (3 entities in total)
• 機能のキーワード: aspartic proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Cryphonectria parasitica (chestnut blight fungus)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34447.67

構造登録者

Blundell, T.L.,Frazao, C.,Cooper, J.B. (登録日: 1992-06-15, 公開日: 1994-01-31, 最終更新日: 2017-11-29)

• 主引用文献: Cooper, J.,Quail, W.,Frazao, C.,Foundling, S.I.,Blundell, T.L.,Humblet, C.,Lunney, E.A.,Lowther, W.T.,Dunn, B.M.; X-ray crystallographic analysis of inhibition of endothiapepsin by cyclohexyl renin inhibitors.; Biochemistry, 31:8142-8150, 1992; PubMed: 1525155; DOI: 10.1021/bi00150a005

実験手法

X-RAY DIFFRACTION (2 Å)