1EBP

COMPLEX BETWEEN THE EXTRACELLULAR DOMAIN OF ERYTHROPOIETIN (EPO) RECEPTOR [EBP] AND AN AGONIST PEPTIDE [EMP1]

1EBP の概要

• エントリーDOI: 10.2210/pdb1ebp/pdb
• 分子名称: EPO RECEPTOR, EPO MIMETICS PEPTIDE 1 (2 entities in total)
• 機能のキーワード: erythropoietin receptor, signal transduction, protein minimization, drug design, cytokine receptor class 1, complex (cytokine receptor-peptide), complex (cytokine receptor-peptide) complex, complex (cytokine receptor/peptide)
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane; Single-pass type I membrane protein. Isoform EPOR-S: Secreted: P19235
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 50849.69

構造登録者

Livnah, O.,Stura, E.A.,Wilson, I.A. (登録日: 1996-05-07, 公開日: 1997-07-29, 最終更新日: 2024-06-05)

• 主引用文献: Livnah, O.,Stura, E.A.,Johnson, D.L.,Middleton, S.A.,Mulcahy, L.S.,Wrighton, N.C.,Dower, W.J.,Jolliffe, L.K.,Wilson, I.A.; Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A.; Science, 273:464-471, 1996; PubMed: 8662530

実験手法

X-RAY DIFFRACTION (2.8 Å)