1EAH
PV2L COMPLEXED WITH ANTIVIRAL AGENT SCH48973
Summary for 1EAH
Entry DOI | 10.2210/pdb1eah/pdb |
Descriptor | POLIOVIRUS TYPE 2 COAT PROTEINS VP1 TO VP4, 1[2-CHLORO-4-METHOXY-PHENYL-OXYMETHYL]-4-[2,6-DICHLORO-PHENYL-OXYMETHYL]-BENZENE, MYRISTIC ACID, ... (7 entities in total) |
Functional Keywords | type 2, lansing, antiviral, picornavirus, mouse neurovirulence, coat protein, icosahedral virus, virus |
Biological source | Human poliovirus 2 More |
Cellular location | Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P06210 P06210 P06210 P06210 |
Total number of polymer chains | 4 |
Total formula weight | 97491.30 |
Authors | Lentz, K.,Arnold, E. (deposition date: 1997-07-22, release date: 1998-09-16, Last modification date: 2023-04-19) |
Primary citation | Lentz, K.N.,Smith, A.D.,Geisler, S.C.,Cox, S.,Buontempo, P.,Skelton, A.,DeMartino, J.,Rozhon, E.,Schwartz, J.,Girijavallabhan, V.,O'Connell, J.,Arnold, E. Structure of poliovirus type 2 Lansing complexed with antiviral agent SCH48973: comparison of the structural and biological properties of three poliovirus serotypes. Structure, 5:961-978, 1997 Cited by PubMed: 9261087DOI: 10.1016/S0969-2126(97)00249-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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