1E3K
Human Progesteron Receptor Ligand Binding Domain in complex with the ligand metribolone (R1881)
Summary for 1E3K
Entry DOI | 10.2210/pdb1e3k/pdb |
Related | 1A28 |
Descriptor | PROGESTERONE RECEPTOR, (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11-TRIEN-3-ONE (3 entities in total) |
Functional Keywords | human progesterone receptor, ligand binding domain |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 60046.43 |
Authors | Matias, P.M.,Donner, P.,Coelho, R.,Thomaz, M.,Peixoto, C.,Macedo, S.,Otto, N.,Joschko, S.,Scholz, P.,Wegg, A.,Basler, S.,Schafer, M.,Egner, U.,Carrondo, M.A. (deposition date: 2000-06-19, release date: 2001-06-14, Last modification date: 2023-12-13) |
Primary citation | Matias, P.M.,Donner, P.,Coelho, R.,Thomaz, M.,Peixoto, C.,Macedo, S.,Otto, N.,Joschko, S.,Scholz, P.,Wegg, A.,Basler, S.,Schafer, M.,Egner, U.,Carrondo, M.A. Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations. J. Biol. Chem., 275:26164-26171, 2000 Cited by PubMed: 10840043DOI: 10.1074/jbc.M004571200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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