1E1Y

Flavopiridol inhibits glycogen phosphorylase by binding at the inhibitor site

Summary for 1E1Y

Entry DOI	10.2210/pdb1e1y/pdb
Related	1A8I 1ABB 1AXR 1B4D 1BX3 1GPA 1GPB 1GPY 1NOI 1NOJ 1NOK 1PYG 2AMV 2GPA 2GPB 2GPN 2PRI 2PRJ 2SKC 2SKD 2SKE 3AMV 3GPB 4GPB 5GPB 6GPB 7GPB 8GPB 9GPB
Descriptor	GLYCOGEN PHOSPHORYLASE, MUSCLE FORM, 2-(2-CHLORO-PHENYL)-5,7-DIHYDROXY-8-(3-HYDROXY-1-METHYL-PIPERIDIN-4-YL)-4H-BENZOPYRAN-4-ONE, PHOSPHITE ION, ... (6 entities in total)
Functional Keywords	allosteric inhibition, transferase
Biological source	ORYCTOLAGUS CUNICULUS (RABBIT)
Total number of polymer chains	1
Total formula weight	98199.31
Authors	Oikonomakos, N.G.,Zographos, S.E.,Skamnaki, V.T.,Tsitsanou, K.E.,Johnson, L.N. (deposition date: 2000-05-11, release date: 2000-05-17, Last modification date: 2023-12-06)
Primary citation	Oikonomakos, N.G.,Schnier, J.B.,Zographos, S.E.,Skamnaki, V.T.,Tsitsanou, K.E.,Johnson, L.N. Flavopiridol Inhibits Glycogen Phosphorylase by Binding at the Inhibitor Site J.Biol.Chem., 275:34566-, 2000 Cited by PubMed: 10924512 DOI: 10.1074/JBC.M004485200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.23 Å)

Structure validation