1DZH

P14-FLUORESCEIN-N135Q-S380C-ANTITHROMBIN-III

1DZH の概要

• エントリーDOI: 10.2210/pdb1dzh/pdb
• 関連するPDBエントリー: 1ANT 1ATH 1BR8 1DZG 2ANT
• 分子名称: ANTITHROMBIN-III, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: blood clotting, serpin
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• 細胞内の位置: Secreted, extracellular space: P01008 P01008
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 101065.79

構造登録者

Mccoy, A.J.,Huntington, J.A.,Carrell, R.W. (登録日: 2000-02-28, 公開日: 2000-05-26, 最終更新日: 2023-12-06)

• 主引用文献: Huntington, J.A.,Mccoy, A.J.,Belzar, K.J.,Pei, X.Y.,Gettins, P.G.W.,Carrell, R.W.; The Conformational Activation of Antithrombin. A 2. 85-A Structure of a Fluorescein Derivative Reveals an Electrostatic Link between the Hinge and Heparin Binding Regions.; J.Biol.Chem., 275:15377-, 2000; PubMed: 10809774; DOI: 10.1074/JBC.275.20.15377

実験手法

X-RAY DIFFRACTION (2.85 Å)