1DS2

CRYSTAL STRUCTURE OF SGPB:OMTKY3-COO-LEU18I

1DS2 の概要

• エントリーDOI: 10.2210/pdb1ds2/pdb
• 関連するPDBエントリー: 1SGP 1SGQ 1SGR 2SGP 3SGB
• 分子名称: PROTEINASE B (SGPB), OVOMUCOID (3 entities in total)
• 機能のキーワード: serine proteinase, protein inhibitor, ovomucoid, canonical inhibitor, ester bond, sgpb, omtky3, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Meleagris gallopavo (turkey); 詳細
• 細胞内の位置: Secreted: P68390
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 24251.56

構造登録者

Bateman, K.S.,Huang, K.,Anderson, S.,Lu, W.,Qasim, M.A.,Laskowski Jr., M.,James, M.N.G. (登録日: 2000-01-06, 公開日: 2001-01-31, 最終更新日: 2021-11-03)

• 主引用文献: Bateman, K.S.,Huang, K.,Anderson, S.,Lu, W.,Qasim, M.A.,Laskowski Jr., M.,James, M.N.; Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I; J.Mol.Biol., 305:839-849, 2001; PubMed: 11162096; DOI: 10.1006/jmbi.2000.4343

実験手法

X-RAY DIFFRACTION (1.7 Å)