1DQN
CRYSTAL STRUCTURE OF GIARDIA GUANINE PHOSPHORIBOSYLTRANSFERASE COMPLEXED WITH A TRANSITION STATE ANALOGUE
Summary for 1DQN
Entry DOI | 10.2210/pdb1dqn/pdb |
Related | 1DQP |
Descriptor | GUANINE PHOSPHORIBOSYLTRANSFERASE, MAGNESIUM ION, PHOSPHORIC ACID MONO-[5-(2-AMINO-4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-3,4-DIHYDROXY-PYRROLIDIN-2-YLMETHYL] ESTER, ... (6 entities in total) |
Functional Keywords | protein-inhibitor complex, mg ions, pyrophosphate, transition state analogue, transferase |
Biological source | Giardia intestinalis |
Total number of polymer chains | 2 |
Total formula weight | 53917.68 |
Authors | Shi, W.,Munagala, N.R.,Wang, C.C.,Li, C.M.,Tyler, P.C.,Furneaux, R.H.,Grubmeyer, C.,Schramm, V.L.,Almo, S.C. (deposition date: 2000-01-04, release date: 2000-07-26, Last modification date: 2024-02-07) |
Primary citation | Shi, W.,Munagala, N.R.,Wang, C.C.,Li, C.M.,Tyler, P.C.,Furneaux, R.H.,Grubmeyer, C.,Schramm, V.L.,Almo, S.C. Crystal structures of Giardia lamblia guanine phosphoribosyltransferase at 1.75 A(,). Biochemistry, 39:6781-6790, 2000 Cited by PubMed: 10841757DOI: 10.1021/bi000128t PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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