1DQD

CRYSTAL STRUCTURE OF FAB HGR-2 F6, A COMPETITIVE ANTAGONIST OF THE GLUCAGON RECEPTOR

1DQD の概要

• エントリーDOI: 10.2210/pdb1dqd/pdb
• 分子名称: FAB HGR-2 F6 (3 entities in total)
• 機能のキーワード: glucagon receptor, monoclonal antibody, fab, receptor antagonist, typical immunoglobulin fold, light chain, heavy chain, antigen binding site, complementarity-determining regions, immune system
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 47846.04

構造登録者

Wright, L.M.,Brzozowski, A.M.,Hubbard, R.E.,Pike, A.C.W.,Roberts, S.M.,Skovgaard, R.N.,Svendsen, I.,Vissing, H.,Bywater, R.P. (登録日: 2000-01-04, 公開日: 2000-05-10, 最終更新日: 2011-07-13)

• 主引用文献: Wright, L.M.,Brzozowski, A.M.,Hubbard, R.E.,Pike, A.C.,Roberts, S.M.,Skovgaard, R.N.,Svendsen, I.,Vissing, H.,Bywater, R.P.; Structure of Fab hGR-2 F6, a competitive antagonist of the glucagon receptor.; Acta Crystallogr.,Sect.D, 56:573-580, 2000; PubMed: 10771426; DOI: 10.1107/S090744490000233X

実験手法

X-RAY DIFFRACTION (2.1 Å)