1DPN

B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE

Summary for 1DPN

• Entry DOI: 10.2210/pdb1dpn/pdb
• Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3'), MAGNESIUM ION (3 entities in total)
• Functional Keywords: 0.95 a resolution structure, dna
• Total number of polymer chains: 2
• Total formula weight: 7459.99

Authors

Egli, M.,Tereshko, V.,Teplova, M.,Minasov, G.,Joachimiak, A.,Sanishvili, R.,Weeks, C.M.,Miller, R.,Maier, M.A.,An, H.,Dan Cook, P.,Manoharan, M. (deposition date: 1999-12-27, release date: 2000-04-04, Last modification date: 2024-02-07)

Primary citation

Egli, M.,Tereshko, V.,Teplova, M.,Minasov, G.,Joachimiak, A.,Sanishvili, R.,Weeks, C.M.,Miller, R.,Maier, M.A.,An, H.,Dan Cook, P.,Manoharan, M.
X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution.
Biopolymers, 48:234-252, 1998

PubMed Abstract: We have determined single crystal structures of an A-DNA decamer and a B-DNA dodecamer at 0.83 and 0.95 A, respectively. The resolution of the former is the highest reported thus far for any right-handed nucleic acid duplex and the quality of the diffraction data allowed determination of the structure with direct methods. The structures reveal unprecedented details of DNA fine structure and hydration; in particular, we have reexamined the overall hydration of A- and B-form DNA, the distribution of water around phosphate groups, and features of the water structure that may underlie the B to A transition.

PubMed: 10699842
DOI: 10.1002/(SICI)1097-0282(1998)48:4<234::AID-BIP4>3.0.CO;2-H

Experimental method

X-RAY DIFFRACTION (0.95 Å)