1DPN

B-DODECAMER CGCGAA(TAF)TCGCG WITH INCORPORATED 2'-DEOXY-2'-FLUORO-ARABINO-FURANOSYL THYMINE

1DPN の概要

• エントリーDOI: 10.2210/pdb1dpn/pdb
• 分子名称: DNA (5'-D(*CP*GP*CP*GP*AP*AP*(TAF)P*TP*CP*GP*CP*G)-3'), MAGNESIUM ION (3 entities in total)
• 機能のキーワード: 0.95 a resolution structure, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 7459.99

構造登録者

Egli, M.,Tereshko, V.,Teplova, M.,Minasov, G.,Joachimiak, A.,Sanishvili, R.,Weeks, C.M.,Miller, R.,Maier, M.A.,An, H.,Dan Cook, P.,Manoharan, M. (登録日: 1999-12-27, 公開日: 2000-04-04, 最終更新日: 2024-02-07)

主引用文献

Egli, M.,Tereshko, V.,Teplova, M.,Minasov, G.,Joachimiak, A.,Sanishvili, R.,Weeks, C.M.,Miller, R.,Maier, M.A.,An, H.,Dan Cook, P.,Manoharan, M.
X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution.
Biopolymers, 48:234-252, 1998

PubMed Abstract: We have determined single crystal structures of an A-DNA decamer and a B-DNA dodecamer at 0.83 and 0.95 A, respectively. The resolution of the former is the highest reported thus far for any right-handed nucleic acid duplex and the quality of the diffraction data allowed determination of the structure with direct methods. The structures reveal unprecedented details of DNA fine structure and hydration; in particular, we have reexamined the overall hydration of A- and B-form DNA, the distribution of water around phosphate groups, and features of the water structure that may underlie the B to A transition.

PubMed: 10699842
DOI: 10.1002/(SICI)1097-0282(1998)48:4<234::AID-BIP4>3.0.CO;2-H

実験手法

X-RAY DIFFRACTION (0.95 Å)