1DIT

COMPLEX OF A DIVALENT INHIBITOR WITH THROMBIN

1DIT の概要

• エントリーDOI: 10.2210/pdb1dit/pdb
• 分子名称: ALPHA-THROMBIN, PEPTIDE INHIBITOR CVS995, ... (4 entities in total)
• 機能のキーワード: hydrolase, blood coagulation, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted, extracellular space: P00734 P00734
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 36010.99

構造登録者

Tulinsky, A.,Krishnan, R. (登録日: 1995-07-20, 公開日: 1996-06-10, 最終更新日: 2023-11-15)

• 主引用文献: Krishnan, R.,Tulinsky, A.,Vlasuk, G.P.,Pearson, D.,Vallar, P.,Bergum, P.,Brunck, T.K.,Ripka, W.C.; Synthesis, structure, and structure-activity relationships of divalent thrombin inhibitors containing an alpha-keto-amide transition-state mimetic.; Protein Sci., 5:422-433, 1996; PubMed: 8868478

実験手法

X-RAY DIFFRACTION (2.3 Å)