1DIR

CRYSTAL STRUCTURE OF A MONOCLINIC FORM OF DIHYDROPTERIDINE REDUCTASE FROM RAT LIVER

1DIR の概要

• エントリーDOI: 10.2210/pdb1dir/pdb
• 分子名称: DIHYDROPTERIDINE REDUCTASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE (3 entities in total)
• 機能のキーワード: oxidoreductase(acting on nadh or nadph)
• 由来する生物種: Rattus norvegicus (Norway rat)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 104970.40

構造登録者

Varughese, K.I.,Su, Y.,Skinner, M.M.,Matthews, D.A.,Whitely, J.M.,Xuong, N.H. (登録日: 1994-04-18, 公開日: 1994-07-31, 最終更新日: 2024-02-07)

主引用文献

Su, Y.,Skinner, M.M.,Xuong, N.H.,Matthews, D.A.,Whiteley, J.M.,Varughese, K.I.
Crystal structure of a monoclinic form of dihydropteridine reductase from rat liver.
Acta Crystallogr.,Sect.D, 50:884-888, 1994

PubMed Abstract: A binary complex of dihydropteridine reductase and NADH crystallizes in the space group C2, with a = 222.2, b = 46.5, c = 95.3 A and beta = 101.1 degrees. There are two dimers in the asymmetric unit. The structure was solved by molecular-replacement techniques and refined with 2.6 A data to a crystallographic R factor of 16.8%. Each dimer has twofold non-crystallographic symmetry and the four individual monomers in the asymmetric unit have the same overall molecular conformation.

PubMed: 15299357
DOI: 10.1107/S0907444994005718

実験手法

X-RAY DIFFRACTION (2.6 Å)