Complex of active site inhibited human blood coagulation factor VIIA with human recombinant soluble tissue factor

Summary for 1DAN

Related PRD IDPRD_000369
DescriptorBLOOD COAGULATION FACTOR VIIA light chain, BLOOD COAGULATION FACTOR VIIA heavy chain, SOLUBLE TISSUE FACTOR, ... (11 entities in total)
Functional Keywordsblood coagulation, serine protease, co-factor, receptor enzyme, gla, egf, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
Cellular locationSecreted P08709 P13726
Isoform 1: Membrane; Single-pass type I membrane protein. Isoform 2: Secreted P08709 P13726
Total number of polymer chains4
Total molecular weight70003.49
Banner, D.W. (deposition date: 1997-03-05, release date: 1997-09-04, Last modification date: 2012-12-12)
Primary citation
Banner, D.W.,D'Arcy, A.,Chene, C.,Winkler, F.K.,Guha, A.,Konigsberg, W.H.,Nemerson, Y.,Kirchhofer, D.
The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor.
Nature, 380:41-46, 1996
PubMed: 8598903 (PDB entries with the same primary citation)
DOI: 10.1038/380041a0
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers50.5%2.6%3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution