1D5A

CRYSTAL STRUCTURE OF AN ARCHAEBACTERIAL DNA POLYMERASE D.TOK. DEPOSITION OF SECOND NATIVE STRUCTURE AT 2.4 ANGSTROM

Summary for 1D5A

• Entry DOI: 10.2210/pdb1d5a/pdb
• Related: 1QQC
• Descriptor: PROTEIN (DNA POLYMERASE), SULFATE ION, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: dna polymerase, thermostable, exonuclease, rbd domain, transferase
• Biological source: Desulfurococcus sp. Tok
• Total number of polymer chains: 1
• Total formula weight: 85819.13

Authors

Zhao, Y.,Jeruzalmi, D.,Leighton, L.,Lasken, R.,Kuriyan, J. (deposition date: 1999-10-06, release date: 2000-03-24, Last modification date: 2024-10-09)

Primary citation

Zhao, Y.,Jeruzalmi, D.,Moarefi, I.,Leighton, L.,Lasken, R.,Kuriyan, J.
Crystal structure of an archaebacterial DNA polymerase.
Structure Fold.Des., 7:1189-1199, 1999

PubMed Abstract: Members of the Pol II family of DNA polymerases are responsible for chromosomal replication in eukaryotes, and carry out highly processive DNA replication when attached to ring-shaped processivity clamps. The sequences of Pol II polymerases are distinct from those of members of the well-studied Pol I family of DNA polymerases. The DNA polymerase from the archaebacterium Desulfurococcus strain Tok (D. Tok Pol) is a member of the Pol II family that retains catalytic activity at elevated temperatures.

PubMed: 10545321
DOI: 10.1016/S0969-2126(00)80053-2

Experimental method

X-RAY DIFFRACTION (2.4 Å)