1D3V

CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH 2(S)-AMINO-6-BORONOHEXANOIC ACID, AN L-ARGININE ANALOG

1D3V の概要

• エントリーDOI: 10.2210/pdb1d3v/pdb
• 分子名称: PROTEIN (ARGINASE), MANGANESE (II) ION, 2(S)-AMINO-6-BORONOHEXANOIC ACID, ... (4 entities in total)
• 機能のキーワード: binuclear manganese cluster, boronic acid inhibitor, perfectly twinned crystal, hydrolase
• 由来する生物種: Rattus norvegicus (Norway rat)
• 細胞内の位置: Cytoplasm: P07824
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 70641.94

構造登録者

Cox, J.D.,Kim, N.N.,Traish, A.M.,Christianson, D.W. (登録日: 1999-10-01, 公開日: 1999-11-17, 最終更新日: 2024-02-07)

• 主引用文献: Cox, J.D.,Kim, N.N.,Traish, A.M.,Christianson, D.W.; Arginase-boronic acid complex highlights a physiological role in erectile function.; Nat.Struct.Biol., 6:1043-1048, 1999; PubMed: 10542097; DOI: 10.1038/14929

実験手法

X-RAY DIFFRACTION (1.7 Å)