1D2L

NMR SOLUTION STRUCTURE OF COMPLEMENT-LIKE REPEAT CR3 FROM THE LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN (LRP). EVIDENCE FOR SPECIFIC BINDING TO THE RECEPTOR BINDING DOMAIN OF HUMAN ALPHA-2 MACROGLOBULIN

1D2L の概要

• エントリーDOI: 10.2210/pdb1d2l/pdb
• 関連するPDBエントリー: 1CR8
• NMR情報: BMRB: 4514
• 分子名称: LIPOPROTEIN RECEPTOR RELATED PROTEIN, CALCIUM ION (2 entities in total)
• 機能のキーワード: ligand binding, calcium binding, complement-like repeat, receptor, signaling protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Low-density lipoprotein receptor-related protein 1 85 kDa subunit: Cell membrane; Single-pass type I membrane protein. Low-density lipoprotein receptor-related protein 1 515 kDa subunit: Cell membrane; Peripheral membrane protein; Extracellular side. Low-density lipoprotein receptor-related protein 1 intracellular domain: Cytoplasm: Q07954
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 4992.43

構造登録者

Dolmer, K.,Huang, W.,Gettins, P.G.W. (登録日: 1999-09-24, 公開日: 2000-01-14, 最終更新日: 2022-12-21)

• 主引用文献: Dolmer, K.,Huang, W.,Gettins, P.G.; NMR solution structure of complement-like repeat CR3 from the low density lipoprotein receptor-related protein. Evidence for specific binding to the receptor binding domain of human alpha(2)-macroglobulin.; J.Biol.Chem., 275:3264-3269, 2000; PubMed: 10652313; DOI: 10.1074/jbc.275.5.3264

実験手法

SOLUTION NMR