1CZQ

CRYSTAL STRUCTURE OF THE D10-P1/IQN17 COMPLEX: A D-PEPTIDE INHIBITOR OF HIV-1 ENTRY BOUND TO THE GP41 COILED-COIL POCKET.

1CZQ の概要

• エントリーDOI: 10.2210/pdb1czq/pdb
• 分子名称: FUSION PROTEIN BETWEEN THE HYDROPHOBIC POCKET OF HIV GP41 AND GCN4-PIQI, D-PEPTIDE INHIBITOR, CHLORIDE ION, ... (4 entities in total)
• 機能のキーワード: envelope glycoprotein, viral protein-inhibitor complex, viral protein/inhibitor
• 由来する生物種: Saccharomyces cerevisiae, Human immunodeficiency virus (baker's yeast,); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 7363.14

構造登録者

Eckert, D.M.,Malashkevich, V.N.,Hong, L.H.,Carr, P.A.,Kim, P.S. (登録日: 1999-09-06, 公開日: 1999-10-13, 最終更新日: 2011-07-13)

• 主引用文献: Eckert, D.M.,Malashkevich, V.N.,Hong, L.H.,Carr, P.A.,Kim, P.S.; Inhibiting HIV-1 entry: discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket.; Cell(Cambridge,Mass.), 99:103-115, 1999; PubMed: 10520998; DOI: 10.1016/S0092-8674(00)80066-5

実験手法

X-RAY DIFFRACTION (1.5 Å)