1CX3

SOLUTION STRUCTURE OF A COMPLEX BETWEEN D(ATGCAT)2 AND THE ANTITUMOR BISNAPHTHALIMIDE LU-79553

1CX3 の概要

• エントリーDOI: 10.2210/pdb1cx3/pdb
• 分子名称: DNA (5'-D(*AP*TP*GP*CP*AP*T)-3'), N,N'-(3,7-DIAZANONYLENE)-BIS-NAPHTHALIMIDE (2 entities in total)
• 機能のキーワード: topoisomerase, anticancer, dna, naphthalimide, intercalation, deoxyribonucleic acid
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 4139.05

構造登録者

Gallego, J.,Reid, B.R. (登録日: 1999-08-27, 公開日: 1999-11-19, 最終更新日: 2022-02-16)

• 主引用文献: Gallego, J.,Reid, B.R.; Solution structure and dynamics of a complex between DNA and the antitumor bisnaphthalimide LU-79553: intercalated ring flipping on the millisecond time scale.; Biochemistry, 38:15104-15115, 1999; PubMed: 10563793; DOI: 10.1021/bi9915869

実験手法

SOLUTION NMR