1CU4
CRYSTAL STRUCTURE OF THE ANTI-PRION FAB 3F4 IN COMPLEX WITH ITS PEPTIDE EPITOPE
Summary for 1CU4
Entry DOI | 10.2210/pdb1cu4/pdb |
Descriptor | FAB LIGHT CHAIN, FAB HEAVY CHAIN, RECOGNITION PEPTIDE, ... (4 entities in total) |
Functional Keywords | immunoglobulin fold, immune system |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 3 |
Total formula weight | 48555.11 |
Authors | Kanyo, Z.F.,Pan, K.M.,Williamson, R.A.,Burton, D.R.,Prusiner, S.B.,Fletterick, R.J.,Cohen, F.E. (deposition date: 1999-08-20, release date: 2000-04-17, Last modification date: 2018-04-04) |
Primary citation | Kanyo, Z.F.,Pan, K.M.,Williamson, R.A.,Burton, D.R.,Prusiner, S.B.,Fletterick, R.J.,Cohen, F.E. Antibody binding defines a structure for an epitope that participates in the PrPC-->PrPSc conformational change. J.Mol.Biol., 293:855-863, 1999 Cited by PubMed: 10543972DOI: 10.1006/jmbi.1999.3193 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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