1CLU
H-RAS COMPLEXED WITH DIAMINOBENZOPHENONE-BETA,GAMMA-IMIDO-GTP
Summary for 1CLU
Entry DOI | 10.2210/pdb1clu/pdb |
Descriptor | TRANSFORMING PROTEIN P21/H-RAS-1, MAGNESIUM ION, 3-AMINOBENZOPHENONE-4-YL-AMINOHYDROXYPHOSPHINYLAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (4 entities in total) |
Functional Keywords | gtp hydrolase, signal transduction, cancer, g-domain, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 19655.99 |
Authors | Ahmadian, M.R.,Zor, T.,Vogt, D.,Kabsch, W.,Selinger, Z.,Wittinghofer, A.,Scheffzek, K. (deposition date: 1999-05-03, release date: 1999-05-28, Last modification date: 2023-08-09) |
Primary citation | Ahmadian, M.R.,Zor, T.,Vogt, D.,Kabsch, W.,Selinger, Z.,Wittinghofer, A.,Scheffzek, K. Guanosine triphosphatase stimulation of oncogenic Ras mutants. Proc.Natl.Acad.Sci.USA, 96:7065-7070, 1999 Cited by PubMed: 10359839DOI: 10.1073/pnas.96.12.7065 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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