1CL7

ANTI HIV1 PROTEASE FAB

Summary for 1CL7

• Entry DOI: 10.2210/pdb1cl7/pdb
• Descriptor: PROTEIN (IGG1 ANTIBODY 1696 (light chain)), PROTEIN (IGG1 ANTIBODY 1696 (variable heavy chain)), PROTEIN (IGG1 ANTIBODY 1696 (constant heavy chain)) (3 entities in total)
• Functional Keywords: fab fragment, cross-reactivity, hiv1 protease, enzyme inhibition, immunoglobulin, immune system
• Biological source: Mus musculus (house mouse); More
• Cellular location: Cell membrane; Single-pass membrane protein (Potential): P01869
• Total number of polymer chains: 3
• Total formula weight: 47660.99

Authors

Lescar, J.,Bentley, G.A. (deposition date: 1999-05-06, release date: 2000-01-12, Last modification date: 2023-08-09)

• Primary citation: Lescar, J.,Brynda, J.,Rezacova, P.,Stouracova, R.,Riottot, M.M.,Chitarra, V.,Fabry, M.,Horejsi, M.,Sedlacek, J.,Bentley, G.A.; Inhibition of the HIV-1 and HIV-2 proteases by a monoclonal antibody.; Protein Sci., 8:2686-2696, 1999; PubMed: 10631984

Experimental method

X-RAY DIFFRACTION (3 Å)