1CIV

CHLOROPLAST NADP-DEPENDENT MALATE DEHYDROGENASE FROM FLAVERIA BIDENTIS

Summary for 1CIV

• Entry DOI: 10.2210/pdb1civ/pdb
• Descriptor: NADP-MALATE DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
• Functional Keywords: chloroplast, light activated, nadp-dependent, dehydrogenase, oxidoreductase
• Biological source: Flaveria bidentis
• Total number of polymer chains: 1
• Total formula weight: 42840.44

Authors

Carr, P.D.,Ashton, A.R.,Verger, D.,Ollis, D.L. (deposition date: 1999-04-01, release date: 2000-04-05, Last modification date: 2024-11-13)

Primary citation

Carr, P.D.,Verger, D.,Ashton, A.R.,Ollis, D.L.
Chloroplast NADP-malate dehydrogenase: structural basis of light-dependent regulation of activity by thiol oxidation and reduction.
Structure Fold.Des., 7:461-475, 1999

PubMed Abstract: NADP-dependent malate dehydrogenase (EC 1.1.1.82) is a light-activated chloroplast enzyme that functions in the C4 pathway of photosynthesis. The light regulation is believed to be mediated in vivo by thioredoxin-catalyzed reduction and re-oxidation of cystine residues. The rates of reversible activation and inactivation of the enzyme are strongly influenced by the coenzyme substrates that seem to ultimately determine the steady-state extent of activation in vivo.

PubMed: 10196131
DOI: 10.1016/S0969-2126(99)80058-6

Experimental method

X-RAY DIFFRACTION (2.8 Å)