1CAQ

X-RAY STRUCTURE OF HUMAN STROMELYSIN CATALYTIC DOMAIN COMPLEXES WITH NON-PEPTIDE INHIBITORS: IMPLICATION FOR INHIBITOR SELECTIVITY

1CAQ の概要

• エントリーDOI: 10.2210/pdb1caq/pdb
• 分子名称: PROTEIN (STROMELYSIN-1), ZINC ION, CALCIUM ION, ... (6 entities in total)
• 機能のキーワード: matrix metalloproteinase, mmp-3, non-peptide inhibitor, hydrolase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted, extracellular space, extracellular matrix : P08254
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 19737.76

構造登録者

Pavlovsky, A.G.,Williams, M.G.,Ye, Q.-Z.,Ortwine, D.F.,Purchase II, C.F.,White, A.D.,Dhanaraj, V.,Roth, B.D.,Johnson, L.L.,Hupe, D.,Humblet, C.,Blundell, T.L. (登録日: 1999-02-23, 公開日: 1999-07-07, 最終更新日: 2023-12-27)

• 主引用文献: Pavlovsky, A.G.,Williams, M.G.,Ye, Q.Z.,Ortwine, D.F.,Purchase II, C.F.,White, A.D.,Dhanaraj, V.,Roth, B.D.,Johnson, L.L.,Hupe, D.,Humblet, C.,Blundell, T.L.; X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity.; Protein Sci., 8:1455-1462, 1999; PubMed: 10422833

実験手法

X-RAY DIFFRACTION (1.8 Å)