1CA0
BOVINE CHYMOTRYPSIN COMPLEXED TO APPI
1CA0 の概要
エントリーDOI | 10.2210/pdb1ca0/pdb |
分子名称 | BOVINE CHYMOTRYPSIN, PROTEASE INHIBITOR DOMAIN OF ALZHEIMER'S AMYLOID BETA-PROTEIN PRECURSOR, ... (5 entities in total) |
機能のキーワード | serine protease, inhibitor, protease-substrate interactions, complex (serine protease-inhibitor), complex (serine protease-inhibitor) complex, complex (serine protease/inhibitor) |
由来する生物種 | Bos taurus (cattle) 詳細 |
細胞内の位置 | Secreted, extracellular space: P00766 P00766 P00766 Membrane; Single-pass type I membrane protein: P05067 |
タンパク質・核酸の鎖数 | 8 |
化学式量合計 | 62536.46 |
構造登録者 | |
主引用文献 | Scheidig, A.J.,Hynes, T.R.,Pelletier, L.A.,Wells, J.A.,Kossiakoff, A.A. Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid beta-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): engineering of inhibitors with altered specificities. Protein Sci., 6:1806-1824, 1997 Cited by PubMed: 9300481主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.1 Å) |
構造検証レポート
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