1C7S
BETA-N-ACETYLHEXOSAMINIDASE MUTANT D539A COMPLEXED WITH DI-N-ACETYL-BETA-D-GLUCOSAMINE (CHITOBIASE)
Summary for 1C7S
Entry DOI | 10.2210/pdb1c7s/pdb |
Related | 1C7T 1QBA 1QBB 1QBC |
Descriptor | BETA-N-ACETYLHEXOSAMINIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (4 entities in total) |
Functional Keywords | glycosyl hydrolase, beta-n-acetylhexosaminidase, chitinolysis, a/b(tim)-barrel, site directed mutagenesis, substrate nucleophile stabilizer mutation, hydrolase |
Biological source | Serratia marcescens |
Cellular location | Periplasm: Q54468 |
Total number of polymer chains | 1 |
Total formula weight | 96749.58 |
Authors | Prag, G.,Papanikolau, Y.,Tavlas, G.,Vorgias, C.E.,Petratos, K.,Oppenheim, A.B. (deposition date: 2000-03-14, release date: 2000-09-20, Last modification date: 2023-08-09) |
Primary citation | Prag, G.,Papanikolau, Y.,Tavlas, G.,Vorgias, C.E.,Petratos, K.,Oppenheim, A.B. Structures of chitobiase mutants complexed with the substrate Di-N-acetyl-d-glucosamine: the catalytic role of the conserved acidic pair, aspartate 539 and glutamate 540. J.Mol.Biol., 300:611-617, 2000 Cited by PubMed: 10884356DOI: 10.1006/jmbi.2000.3906 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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