1C7S

BETA-N-ACETYLHEXOSAMINIDASE MUTANT D539A COMPLEXED WITH DI-N-ACETYL-BETA-D-GLUCOSAMINE (CHITOBIASE)

1C7S の概要

• エントリーDOI: 10.2210/pdb1c7s/pdb
• 関連するPDBエントリー: 1C7T 1QBA 1QBB 1QBC
• 分子名称: BETA-N-ACETYLHEXOSAMINIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: glycosyl hydrolase, beta-n-acetylhexosaminidase, chitinolysis, a/b(tim)-barrel, site directed mutagenesis, substrate nucleophile stabilizer mutation, hydrolase
• 由来する生物種: Serratia marcescens
• 細胞内の位置: Periplasm: Q54468
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 96749.58

構造登録者

Prag, G.,Papanikolau, Y.,Tavlas, G.,Vorgias, C.E.,Petratos, K.,Oppenheim, A.B. (登録日: 2000-03-14, 公開日: 2000-09-20, 最終更新日: 2023-08-09)

• 主引用文献: Prag, G.,Papanikolau, Y.,Tavlas, G.,Vorgias, C.E.,Petratos, K.,Oppenheim, A.B.; Structures of chitobiase mutants complexed with the substrate Di-N-acetyl-d-glucosamine: the catalytic role of the conserved acidic pair, aspartate 539 and glutamate 540.; J.Mol.Biol., 300:611-617, 2000; PubMed: 10884356; DOI: 10.1006/jmbi.2000.3906

実験手法