1C74

Structure of the double mutant (K53,56M) of phospholipase A2

Summary for 1C74

• Entry DOI: 10.2210/pdb1c74/pdb
• Related: 1MKT
• Descriptor: PHOSPHOLIPASE A2, CALCIUM ION (3 entities in total)
• Functional Keywords: alpha helix, beta sheet, double mutant, hydrolase
• Biological source: Bos taurus (cattle)
• Cellular location: Secreted: P00593
• Total number of polymer chains: 1
• Total formula weight: 13854.61

Authors

Sekar, K.,Tsai, M.D.,Jain, M.K.,Ramakumar, S. (deposition date: 2000-01-22, release date: 2000-07-22, Last modification date: 2023-08-09)

• Primary citation: Yu, B.Z.,Poi, M.J.,Ramagopal, U.A.,Jain, R.,Ramakumar, S.,Berg, O.G.,Tsai, M.D.,Sekar, K.,Jain, M.K.; Structural basis of the anionic interface preference and k*cat activation of pancreatic phospholipase A2.; Biochemistry, 39:12312-12323, 2000; PubMed: 11015210; DOI: 10.1021/bi000740k

Experimental method

X-RAY DIFFRACTION (1.9 Å)