1BZH

Cyclic peptide inhibitor of human PTP1B

1BZH の概要

• エントリーDOI: 10.2210/pdb1bzh/pdb
• 分子名称: PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE 1B), PROTEIN (PROTEIN-TYROSINE-PHOSPHATASE 1B INHIBITOR) (3 entities in total)
• 機能のキーワード: phosphorylation-inhibitor complex, tyrosine phosphatase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 35725.51

構造登録者

Groves, M.R.,Yao, Z.J.,Burke Jr., T.R.,Barford, D. (登録日: 1998-10-28, 公開日: 1999-02-16, 最終更新日: 2023-11-15)

• 主引用文献: Groves, M.R.,Yao, Z.J.,Roller, P.P.,Burke Jr., T.R.,Barford, D.; Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics.; Biochemistry, 37:17773-17783, 1998; PubMed: 9922143; DOI: 10.1021/bi9816958

実験手法

X-RAY DIFFRACTION (2.1 Å)