1BVE
HIV-1 PROTEASE-DMP323 COMPLEX IN SOLUTION, NMR, 28 STRUCTURES
Summary for 1BVE
Entry DOI | 10.2210/pdb1bve/pdb |
Related | 1BVG |
Descriptor | HIV-1 PROTEASE, [4-R-(-4-ALPHA,5-ALPHA,6-BETA,7-BETA)]-HEXAHYDRO-5,6-BIS(HYDROXY)-[1,3-BIS([4-HYDROXYMETHYL-PHENYL]METHYL)-4,7-BIS(PHEN YLMETHYL)]-2H-1,3-DIAZEPINONE (2 entities in total) |
Functional Keywords | aids, polyprotein, hydrolase, aspartyl protease, endonuclease, rna-directed dna polymerase |
Biological source | Human immunodeficiency virus 1 |
Cellular location | Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P04585 |
Total number of polymer chains | 2 |
Total formula weight | 22082.02 |
Authors | Yamazaki, T.,Hinck, A.P.,Wang, Y.-X.,Nicholson, L.K.,Torchia, D.A.,Wingfield, P.,Stahl, S.J.,Kaufman, J.D.,Chang, C.,Domaille, P.J.,Lam, P.Y.S. (deposition date: 1996-01-16, release date: 1996-08-17, Last modification date: 2024-05-22) |
Primary citation | Yamazaki, T.,Hinck, A.P.,Wang, Y.X.,Nicholson, L.K.,Torchia, D.A.,Wingfield, P.,Stahl, S.J.,Kaufman, J.D.,Chang, C.H.,Domaille, P.J.,Lam, P.Y. Three-dimensional solution structure of the HIV-1 protease complexed with DMP323, a novel cyclic urea-type inhibitor, determined by nuclear magnetic resonance spectroscopy. Protein Sci., 5:495-506, 1996 Cited by PubMed: 8868486PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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