1BKR

CALPONIN HOMOLOGY (CH) DOMAIN FROM HUMAN BETA-SPECTRIN AT 1.1 ANGSTROM RESOLUTION

Summary for 1BKR

Entry DOI	10.2210/pdb1bkr/pdb
Descriptor	SPECTRIN BETA CHAIN (2 entities in total)
Functional Keywords	filamentous actin-binding domain, cytoskeleton, actin-binding
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	12715.50
Authors	Djinovic Carugo, K.,Banuelos, S.,Saraste, M. (deposition date: 1998-07-10, release date: 1998-07-15, Last modification date: 2024-02-07)
Primary citation	Banuelos, S.,Saraste, M.,Carugo, K.D. Structural comparisons of calponin homology domains: implications for actin binding. Structure, 6:1419-1431, 1998 Cited by PubMed Abstract: The actin-binding site of several cytoskeletal proteins is comprised of two calponin homology (CH) domains in a tandem arrangement. As a single copy, the CH domain is also found in regulatory proteins in muscle and in signal-transduction proteins. The three-dimensional structures of three CH domains are known, but they have not yet clarified the molecular details of the interaction between actin filaments and proteins harbouring CH domains. PubMed: 9817844 DOI: 10.1016/S0969-2126(98)00141-5 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.1 Å)

Structure validation