1BKR

CALPONIN HOMOLOGY (CH) DOMAIN FROM HUMAN BETA-SPECTRIN AT 1.1 ANGSTROM RESOLUTION

1BKR の概要

• エントリーDOI: 10.2210/pdb1bkr/pdb
• 分子名称: SPECTRIN BETA CHAIN (2 entities in total)
• 機能のキーワード: filamentous actin-binding domain, cytoskeleton, actin-binding
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 12715.50

構造登録者

Djinovic Carugo, K.,Banuelos, S.,Saraste, M. (登録日: 1998-07-10, 公開日: 1998-07-15, 最終更新日: 2024-02-07)

主引用文献

Banuelos, S.,Saraste, M.,Carugo, K.D.
Structural comparisons of calponin homology domains: implications for actin binding.
Structure, 6:1419-1431, 1998

PubMed Abstract: The actin-binding site of several cytoskeletal proteins is comprised of two calponin homology (CH) domains in a tandem arrangement. As a single copy, the CH domain is also found in regulatory proteins in muscle and in signal-transduction proteins. The three-dimensional structures of three CH domains are known, but they have not yet clarified the molecular details of the interaction between actin filaments and proteins harbouring CH domains.

PubMed: 9817844
DOI: 10.1016/S0969-2126(98)00141-5

実験手法

X-RAY DIFFRACTION (1.1 Å)