1BKF
FK506 BINDING PROTEIN FKBP MUTANT R42K/H87V COMPLEX WITH IMMUNOSUPPRESSANT FK506
Summary for 1BKF
| Entry DOI | 10.2210/pdb1bkf/pdb |
| Descriptor | FK506 BINDING PROTEIN, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN (3 entities in total) |
| Functional Keywords | isomerase, rotamase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm, cytosol : P62942 |
| Total number of polymer chains | 1 |
| Total formula weight | 12573.50 |
| Authors | Itoh, S.,Decenzo, M.T.,Livingston, D.J.,Pearlman, D.A.,Navia, M.A. (deposition date: 1995-10-18, release date: 1996-08-01, Last modification date: 2024-02-07) |
| Primary citation | Itoh, S.,Decenzo, M.T.,Livingston, D.J.,Pearlman, D.A.,Navia, M.A. Conformation of Fk506 in X-Ray Structures of its Complexes with Human Recombinant Fkbp12 Mutants Bioorg.Med.Chem.Lett., 5:1983-, 1995 Cited by |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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