1BJI
THE X-RAY STRUCTURE OF A COMPLEX OF TERN N9 INFLUENZA VIRUS NEURAMINIDASE COMPLEXED WITH THE GLAXO 6-CARBOXAMIDE SIALIC ACID ANALOGUE GR217029
1BJI の概要
エントリーDOI | 10.2210/pdb1bji/pdb |
分子名称 | NEURAMINIDASE, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose, ... (7 entities in total) |
機能のキーワード | neuraminidase, influenza protein, inhibitor complex, 6-carboxamide derivative, sialic acid analogue, glaxo gr217029, hydrolase, glycoprotein |
由来する生物種 | Influenza A virus |
細胞内の位置 | Virion membrane (By similarity): P03472 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 45848.83 |
構造登録者 | |
主引用文献 | Taylor, N.R.,Cleasby, A.,Singh, O.,Skarzynski, T.,Wonacott, A.J.,Smith, P.W.,Sollis, S.L.,Howes, P.D.,Cherry, P.C.,Bethell, R.,Colman, P.,Varghese, J. Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B. J.Med.Chem., 41:798-807, 1998 Cited by PubMed: 9526556DOI: 10.1021/jm9703754 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2 Å) |
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