1BIU

HIV-1 INTEGRASE CORE DOMAIN COMPLEXED WITH MG++

1BIU の概要

• エントリーDOI: 10.2210/pdb1biu/pdb
• 分子名称: HIV-1 INTEGRASE, MAGNESIUM ION (3 entities in total)
• 機能のキーワード: dna integration, integrase, hiv, hydrolase, aspartyl protease, endonuclease
• 由来する生物種: Human immunodeficiency virus 1
• 細胞内の位置: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 54443.83

構造登録者

Goldgur, Y.,Dyda, F.,Hickman, A.B.,Jenkins, T.M.,Craigie, R.,Davies, D.R. (登録日: 1998-06-19, 公開日: 1998-08-19, 最終更新日: 2024-05-22)

• 主引用文献: Goldgur, Y.,Dyda, F.,Hickman, A.B.,Jenkins, T.M.,Craigie, R.,Davies, D.R.; Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium.; Proc.Natl.Acad.Sci.USA, 95:9150-9154, 1998; PubMed: 9689049; DOI: 10.1073/pnas.95.16.9150

実験手法

X-RAY DIFFRACTION (2.5 Å)