1BHX

X-RAY STRUCTURE OF THE COMPLEX OF HUMAN ALPHA THROMBIN WITH THE INHIBITOR SDZ 229-357

1BHX の概要

• エントリーDOI: 10.2210/pdb1bhx/pdb
• 分子名称: ALPHA THROMBIN, 5-OXO-6-PHENYLMETHANESULFONYLAMINO-HEXAHYDRO-THIAZOLO[3,2-A]PYRIDINE-3-CARBOXYLIC ACID (3-GUANIDINO-PROPYL)-AMIDE, ... (6 entities in total)
• 機能のキーワード: serine protease
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted, extracellular space: P00734 P00734 P00734
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 33622.49

構造登録者

Kallen, J. (登録日: 1998-06-10, 公開日: 1998-11-04, 最終更新日: 2023-08-02)

• 主引用文献: Wagner, J.,Kallen, J.,Ehrhardt, C.,Evenou, J.P.,Wagner, D.; Rational design, synthesis, and X-ray structure of selective noncovalent thrombin inhibitors.; J.Med.Chem., 41:3664-3674, 1998; PubMed: 9733491; DOI: 10.1021/jm981013e

実験手法

X-RAY DIFFRACTION (2.3 Å)