1BHL

CACODYLATED CATALYTIC DOMAIN OF HIV-1 INTEGRASE

1BHL の概要

• エントリーDOI: 10.2210/pdb1bhl/pdb
• 分子名称: HIV-1 INTEGRASE (2 entities in total)
• 機能のキーワード: dna integration, aids, polyprotein, hydrolase, endonuclease, polynucleotidyl transferase, dna binding (viral)
• 由来する生物種: Human immunodeficiency virus 1
• 細胞内の位置: Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16756.84

構造登録者

Maignan, S.,Guilloteau, J.P.,Zhou-Liu, Q.,Clement-Mella, C.,Mikol, V. (登録日: 1998-06-10, 公開日: 1998-10-14, 最終更新日: 2023-08-02)

• 主引用文献: Maignan, S.,Guilloteau, J.P.,Zhou-Liu, Q.,Clement-Mella, C.,Mikol, V.; Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases.; J.Mol.Biol., 282:359-368, 1998; PubMed: 9735293; DOI: 10.1006/jmbi.1998.2002

実験手法

X-RAY DIFFRACTION (2.2 Å)