1BFC

BASIC FIBROBLAST GROWTH FACTOR COMPLEXED WITH HEPARIN HEXAMER FRAGMENT

Summary for 1BFC

Entry DOI	10.2210/pdb1bfc/pdb
Descriptor	BASIC FIBROBLAST GROWTH FACTOR, 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose (3 entities in total)
Functional Keywords	growth factor, mitogen, vascularization, heparin-binding
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	18249.29
Authors	Faham, S.,Rees, D.C. (deposition date: 1995-12-12, release date: 1996-04-03, Last modification date: 2024-02-07)
Primary citation	Faham, S.,Hileman, R.E.,Fromm, J.R.,Linhardt, R.J.,Rees, D.C. Heparin structure and interactions with basic fibroblast growth factor. Science, 271:1116-1120, 1996 Cited by PubMed: 8599088 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation