1BCU

ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND PROFLAVIN

Summary for 1BCU

• Entry DOI: 10.2210/pdb1bcu/pdb
• Descriptor: ALPHA-THROMBIN, HIRUGEN, PROFLAVIN, ... (5 entities in total)
• Functional Keywords: complex (serine protease inhibitor), hydrolase, serine protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Hirudo medicinalis (medicinal leech); More
• Cellular location: Secreted, extracellular space: P00734 P00734; Secreted: P01050
• Total number of polymer chains: 3
• Total formula weight: 35634.58

Authors

Conti, E.,Rivetti, C.,Wonacott, A.,Brick, P. (deposition date: 1998-05-02, release date: 1998-10-14, Last modification date: 2023-08-02)

• Primary citation: Conti, E.,Rivetti, C.,Wonacott, A.,Brick, P.; X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human alpha-thrombin.; FEBS Lett., 425:229-233, 1998; PubMed: 9559654; DOI: 10.1016/S0014-5793(98)00235-X

Experimental method

X-RAY DIFFRACTION (2 Å)