1B9T
NOVEL AROMATIC INHIBITORS OF INFLUENZA VIRUS NEURAMINIDASE MAKE SELECTIVE INTERACTIONS WITH CONSERVED RESIDUES AND WATER MOLECULES IN THE ACTIVE SITE
1B9T の概要
エントリーDOI | 10.2210/pdb1b9t/pdb |
分子名称 | PROTEIN (NEURAMINIDASE), 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (5 entities in total) |
機能のキーワード | influenza, neuraminidase, sialidase, inhibitor, b/lee/40, hydrolase |
由来する生物種 | Influenza B virus (B/Lee/40) |
細胞内の位置 | Virion membrane (By similarity): P03474 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 44084.03 |
構造登録者 | Finley, J.B.,Atigadda, V.R.,Duarte, F.,Zhao, J.J.,Brouillette, W.J.,Air, G.M.,Luo, M. (登録日: 1999-02-15, 公開日: 1999-02-27, 最終更新日: 2023-08-09) |
主引用文献 | Finley, J.B.,Atigadda, V.R.,Duarte, F.,Zhao, J.J.,Brouillette, W.J.,Air, G.M.,Luo, M. Novel aromatic inhibitors of influenza virus neuraminidase make selective interactions with conserved residues and water molecules in the active site. J.Mol.Biol., 293:1107-1119, 1999 Cited by PubMed: 10547289DOI: 10.1006/jmbi.1999.3180 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.4 Å) |
構造検証レポート
検証レポート(詳細版)
をダウンロード
![ダウンロード](/newweb/media/icons/dl.png)