1B9F

MOBILITY OF AN HIV-1 INTEGRASE ACTIVE SITE LOOP IS CORRELATED WITH CATALYTIC ACTIVITY

1B9F の概要

• エントリーDOI: 10.2210/pdb1b9f/pdb
• 分子名称: PROTEIN (INTEGRASE), CACODYLATE ION, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: dna integration, transferase
• 由来する生物種: Human immunodeficiency virus type 1 (CLONE 12)
• 細胞内の位置: Gag-Pol polyprotein: Host cell membrane; Lipid-anchor . Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P12497
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18310.57

構造登録者

Greenwald, J.,Le, V.,Butler, S.L.,Bushman, F.D.,Choe, S. (登録日: 1999-02-11, 公開日: 1999-07-19, 最終更新日: 2023-12-27)

• 主引用文献: Greenwald, J.,Le, V.,Butler, S.L.,Bushman, F.D.,Choe, S.; The mobility of an HIV-1 integrase active site loop is correlated with catalytic activity.; Biochemistry, 38:8892-8898, 1999; PubMed: 10413462; DOI: 10.1021/bi9907173

実験手法

X-RAY DIFFRACTION (1.7 Å)