1B9A

PARVALBUMIN (MUTATION;D51A, F102W)

Summary for 1B9A

Entry DOI	10.2210/pdb1b9a/pdb
Descriptor	PROTEIN (PARVALBUMIN), CALCIUM ION (3 entities in total)
Functional Keywords	calcium binding protein, ef-hand proteins, parvalbumin, calcium-binding
Biological source	Cyprinus carpio (common carp)
Total number of polymer chains	1
Total formula weight	11525.97
Authors	Cates, M.S.,Berry, M.B.,Ho, E.L.,Li, Q.,Potter, J.D.,Phillips Jr., G.N. (deposition date: 1999-02-10, release date: 1999-02-15, Last modification date: 2023-08-09)
Primary citation	Cates, M.S.,Berry, M.B.,Ho, E.L.,Li, Q.,Potter, J.D.,Phillips Jr., G.N. Metal-ion affinity and specificity in EF-hand proteins: coordination geometry and domain plasticity in parvalbumin. Structure Fold.Des., 7:1269-1278, 1999 Cited by PubMed Abstract: The EF-hand family is a large set of Ca(2+)-binding proteins that contain characteristic helix-loop-helix binding motifs that are highly conserved in sequence. Members of this family include parvalbumin and many prominent regulatory proteins such as calmodulin and troponin C. EF-hand proteins are involved in a variety of physiological processes including cell-cycle regulation, second messenger production, muscle contraction, microtubule organization and vision. PubMed: 10545326 DOI: 10.1016/S0969-2126(00)80060-X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation